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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Inflamm Bowel Dis. 2016 Aug;22(8):1793–1802. doi: 10.1097/MIB.0000000000000823

FIGURE 1.

FIGURE 1

Appearance of colonic mucosa and 5-ASA metabolism in Nat1/2 KO mice. (A) Representative images of hematoxylin and eosin stained distal colon in Nat1/2 WT and KO mice. Low resolution (4x) and high resolution (10x) of area indicated by rectangle in low resolution image. Bar = 0.2 mm (B) Representative traces of NAT enzyme activity show fluorescence (Ac-5-ASA: 312 nm excitation/ 437 nm emission) over 120 seconds of Nat1/2 WT (●) or Nat1/2 KO (□) mice distal colon homogenate immediately after the addition of 5-ASA and AcCoA.