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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2016 May 24;9(4):364–371. doi: 10.1161/CIRCOUTCOMES.115.002418

Table 2.

Sociodemographic and Clinical Characteristics Associated with Changing from Nonadherent to Statins before Hospitalization for Acute Myocardial Infarction to Adherent to Statins After Hospital Discharge (N=2,408).*

Characteristic Unadjusted
RR (95% CI)
Adjusted
RR (95% CI)
Age, in years
 65–74 1 (ref) 1 (ref)
 75–84 1.07 (0.96 , 1.20 ) 1.07 (0.96 , 1.20 )
 85+ 0.97 (0.83 , 1.13 ) 0.96 (0.82 , 1.13 )
Female gender 1.00 (0.90 , 1.11 ) 1.01 (0.90 , 1.12 )
Non-white race/ethnicity 0.85 (0.74 , 0.98 ) 0.86 (0.73 , 1.01 )
Eligible for low-income subsidy 0.99 (0.89 , 1.10 ) 1.13 (1.01 , 1.27 )
Urban residence 1.00 (0.90 , 1.12 ) 1.01 (0.90 , 1.13 )
Area-level income, $
 <30,000 1 (ref) 1 (ref)
 30,000-<75,000 1.13 (1.00 , 1.28 ) 1.09 (0.96 , 1.24 )
 75,000+ 1.25 (1.00 , 1.55 ) 1.26 (1.00 , 1.59 )
Comorbidity
 Coronary heart disease 0.79 (0.72 , 0.88 ) 0.81 (0.73 , 0.91 )
 Diabetes mellitus 0.82 (0.74 , 0.91 ) 0.87 (0.78 , 0.97 )
 Chronic kidney disease 0.86 (0.76 , 0.98 ) 0.91 (0.79 , 1.05 )
 Depression 0.88 (0.75 , 1.04 ) 0.89 (0.75 , 1.06 )
 Dementia 0.86 (0.71 , 1.03 ) 0.85 (0.70 , 1.03 )
Number of medication classes before MI
 <5 1 (ref) 1 (ref)
 5 – 9 0.83 (0.68 , 1.01 ) 0.88 (0.72 , 1.08 )
 ≥10 0.75 (0.62 , 0.90 ) 0.85 (0.69 , 1.04 )
Before hospitalization PDC<50% 0.72 (0.64 , 0.80 ) 0.71 (0.63 , 0.79 )
CABG during hospitalization 1.14 (0.96 , 1.35 ) 1.02 (0.86 , 1.21 )
Receive home health services 0.99 (0.87 , 1.12 ) 1.14 (0.99 , 1.30 )

Abbreviations: RR, relative risk; AMI, acute myocardial infarction; PDC, proportion of days covered; CABG, coronary artery bypass graft surgery

*

Analyses were conducted using the primary definition of adherence in which patients were categorized as adherent if PDC ≥80%.

Adjusted analyses include all the variables listed in the table.