Table 3.
Change in Mean Adherence to Statins from Before to After Acute Myocardial Infarction Hospitalization, Pneumonia Hospitalization, and No Hospitalization in Patients Who Were Nonadherent in the First Time Period, and in Patients Who Were Adherent in the First Time Period*
| Nonadherent to Statins (PDC <80%) in First Time Period | |||
|---|---|---|---|
| AMI hospitalization (N=2,408) | Pneumonia hospitalization (N=3,624) | No hospitalization in 2010 - 2011 (N=44,815) | |
| Pre-hospitalization adherence, mean PDC (SD) | 51.1% (21.0%) | 52% (21%) | 53.3% (20.0%) |
| Post-hospitalization adherence, mean PDC (SD) | 61.1% (32.1%) | 45.6% (34.7%) | 48.0% (31.9%) |
| Change in adherence, [post minus pre- hospitalization PDC (95%CI)]† | 10.0% (8.8%, 11.1%) | −6.0% (−6.9%, −5%) | −5.3% (−5.5%, −5.1%) |
| Adherent to Statins (PDC ≥80%) in First Time Period | |||
|---|---|---|---|
| AMI hospitalization (N=4,210) | Pneumonia hospitalization (N=7,847) | No hospitalization in 2010 - 2011 (N=113,284) | |
| Pre-hospitalization adherence, mean PDC (SD) | 94.4% (5.5%) | 94.6% (5.5%) | 95.0% (5.3% ) |
| Post-hospitalization adherence, mean PDC (SD) | 80.6% (22.2%) | 77.7% (24.7%) | 84.1% (17.4%) |
| Change in adherence [post minus pre- hospitalization PDC (95%CI)]‡ | −13.8% (−14.3%, − 13.2%) | −16.9% (−17.4%, − 16.5%) | −11.0% (−11.1%, − 10.9%) |
Abbreviations: AMI, acute myocardial infarction; PDC, proportion of days covered
Proportion of days covered with statins is presented as a continuous measure in this table. The first time period refers to the one year period before the first hospitalization for AMI or pneumonia among patients with this type of hospitalization between 2007 and 2011 or to the one year period spanning 2010 for patients with no hospitalizations in 2010 and 2011.
P-interaction <0.001 comparing all three groups. P-interaction <0.001 for the pairwise comparison of pneumonia hospitalization with AMI hospitalization, and no hospitalization with AMI hospitalization. P-interaction=0.11 for the pairwise comparison of no hospitalization with pneumonia hospitalization.
P-interaction <0.001 comparing all three groups. P-interaction <0.001 for the pairwise comparison of pneumonia hospitalization with AMI hospitalization, no hospitalization with AMI hospitalization and no hospitalization with pneumonia hospitalization.