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. Author manuscript; available in PMC: 2016 Nov 12.
Published in final edited form as: Genes Immun. 2016 May 12;17(5):283–297. doi: 10.1038/gene.2016.19

Table 2.

Canonical pathway mapping of genes marked with H3K4me at rest in naïve and memory CD4 T cells using Ingenuity Pathway Analysis. Specific gene lists for each pathway are reported in Supplementary Table S4.

Pathway # H3K4me2 in Naïve Only H3K4me3 in Memory Only

1 T Cell Receptor signaling G protein signaling
2 Phospholipase C signaling CXCR4 signaling
3 PI3K signaling Role of NFAT in the immune response
4 Role of NFAT in the immune response IL-2 signaling
5 CD28 signaling in T helper cells IL-1 signaling