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. Author manuscript; available in PMC: 2017 Jul 19.
Published in final edited form as: Immunity. 2016 Jul 12;45(1):159–171. doi: 10.1016/j.immuni.2016.06.013

Figure 4. The CXCR3+KLRG1+ subset was enriched with proliferating cells and had characteristics of memory and effector cells.

Figure 4

(A and B) Flow cytometric analysis of splenic GRA6:Ld-tetramer+ CD8+ T cells from infected mice. Data points from the same animal are indicated by connecting lines. Each symbol indicates value from an individual mouse. (A) The percentages of Ki67+ (left), CD71+CD98+ (middle) and EdU+ (right) cells within the indicated subset defined by CXCR3 and KLRG1 expression 60 days after infection. (B) The mean fluorescent intensity (MFI) of Bcl-2 staining in the indicated splenic GRA6:Ld-tetramer+ subsets at ≥ 40 days after infection. (C) Representative histograms showing expression of memory and effector T cell markers in the indicated splenic GRA6:Ld-specific subsets 60 days after infection. All panels are summary of 3-6 independent experiments per group. *P < 0.05, **P < 0.01, and ***P < 0.001 (one-way ANOVA with Tukey's post test).