Table 1.
Baseline characteristics of study subjects.
| N | Mean (SD) or n (%) | |
|---|---|---|
|
| ||
| Age at time of manometry, years | 74 | 50.5 (12.4) |
|
| ||
| Sex, n (% women) | 74 | 62 (84) |
|
| ||
| BMI, kg/m2 | 73 | 25.4 (5.9) |
|
| ||
| Race, n (% white) | 74 | 53 (72) |
|
| ||
| SSc Disease subtype | ||
| n (% diffuse) | 23 (31) | |
| n (% limited) | 74 | 34 (46) |
| n (% SSS) | 6 (8) | |
| n (% other | 10 (14) | |
|
| ||
| Modified Rodnan Skin Score | 52 | 10.4 (11.4) |
|
| ||
| Duration since first Raynaud, months | 67 | 111.4 (119.4) |
|
| ||
| Duration since first non-Raynaud, months | 70 | 81.7 (84.9) |
|
| ||
| On PPI | 74 | 73 (99) |
|
| ||
| Serum autoantibodies, n (% positive) | ||
| Anti-nuclear antibody (ANA) | 67 | 65 (97) |
| Anti-centromere antibody (ACA) | 64 | 13 (20) |
| Scl-70 | 65 | 23 (35) |
| RNA polymerase III | 52 | 5 (10) |
|
| ||
| Pulmonary Function Tests, mean (SD) | ||
| FVC % predicted | 46 | 77.2 (20.5) |
| DLCO % predicted | 46 | 58.1 (20.4) |
|
| ||
| ILD, n (% present) | 63 | 42 (67) |
|
| ||
| Symptoms, n (% positive) | ||
| Dysphagia | 74 | 60 (81) |
| Reflux (heartburn or regurgitation) | 74 | 61 (82) |
Patients with esophageal motility diagnosis of absent contractility, ineffective esophageal motility, and normal esophageal motility are included. BMI – body mass index. PPI – proton pump inhibitor. FVC – forced vital capacity. DLCO – diffusing capacity for carbon monoxide. ILD – interstitial lung disease.