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. 2016 Jul 22;20(8):1561–1570. doi: 10.1111/jcmm.12907

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© 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Disturbed glucose tolerance after knockdown of Brd7 and a high fat diet (HFD) feeding. Wild‐type male mice were fed on HFD for 3 weeks, followed by tail vein injection of Ad‐BRD7shRNA (n = 6) or Ad‐LacZshRNA (n = 6). (A) Fed blood glucose concentrations on day 3 after injection. (B) Fed blood glucose levels on day 6 after injection. (C) Blood glucose levels on day 4 of injection at 16 hours of fasting. (D) Body weights on day 7. (E) GTT on day 4 (left) and AUC (right). Significance in was determined by two‐way anova and Sidak's multiple comparison in (E) or Student's t‐test in (A–E). *P < 0.05, ***P < 0.001.