Figure 4. Comparison of pyocin S5 and tobramycin efficacy.

Bacterial counts were determined by CFU counts of homogenised lungs. (a) Mice treated 1 h post-infection, S5–750 pg and tobramycin–7.5 μg mice survived to 24 h. All other mice culled 5.5 h post-infection. Bars represent Mean ± SEM. *Denotes statistical significance for comparison of treatment versus control by a one-sided Mann-Whitney U test with Bonferroni correction applied.