. 2016 Jul 22;6:30220. doi: 10.1038/srep30220

Table 4. Summary of the corrected P value for multiple testing and heterogeneity test in this meta-analysis.

	No.	Sample size (N)		DD+DI vs. II			DD vs. DI+II			DD vs. II			DI vs. II			D vs. I
	No.	Case	Control	P_Corr^a	I²(%)^b	P_Het ^c	P_Corr^a	I²(%)^b	P_Het ^c	P_Corr^a	I²(%)^b	P_Het ^c	P_Corr^a	I²(%)^b	P_Het ^c	P_Corr^a	I²(%)^b	P_Het^c
Overall	42	18,222	24,778	0.005	77.1	<0.0001	0.0037	80.2	<0.0001	0.005	83.8	<0.0001	0.011	64.1	<0.0001	0.005	84	<0.0001
Control source
PB	10	5,369	8,212	0.443	86.6	<0.0001	0.1	81.5	<0.0001	0.133	83.1	<0.0001	0.689	71.3	<0.0001	0.25	87.8	<0.0001
HB	29	12,463	15,976	0.015	73.3	<0.0001	0.04	77.5	<0.0001	0.0088	79.1	<0.0001	0.01	53.9	<0.0001	0.01	81.2	<0.0001
Ethnicity
Caucasian	12	3,413	6,887	<0.001	35.3	0.108	0.583	21.8	0.229	0.0375	31.9	0.136	<0.001	32.8	0.128	0.0017	32	0.135
Asian	30	14,809	17,891	<0.001	74	<0.0001	0.001	84.5	<0.0001	<0.001	86.3	<0.0001	<0.001	46.5	0.003	<0.001	81.1	<0.0001
Genotyping methods
PCR-RFLP	11	5,450	6,525	0.0025	73.6	<0.0001	0.003	71.9	<0.0001	0.005	78.9	<0.0001	0.005	55.7	0.012	0.002	80.6	<0.0001
MassARRAY	3	998	1,096	0.835	86.7	0.001	0.862	89	<0.0001	1.000	89.1	<0.0001	0.555	65	0.057	0.761	88	<0.0001
TaqMan	14	8,505	12,059	1.000	78.4	<0.0001	0.977	84.2	<0.0001	1.000	85.1	<0.0001	1.000	69	<0.0001	0.856	85.2	<0.0001
PCR-PAGE	6	1,284	1,599	0.1	70.1	0.005	0.01	39.5	0.142	0.02	67.1	0.01	0.257	58.6	0.034	0.025	72.1	0.003
PCR-CGE	2	241	349	0.0925	0	0.722	0.239	55.7	0.133	0.16	43.6	0.183	0.218	0	0.879	0.085	13.4	0.283
Pyrosequencing	4	593	1,228	0.365	12.4	0.331	0.756	6.9	0.358	0.866	0	0.402	0.625	27.7	0.246	0.607	0	0.472
Quality score
<7 points	24	8,849	13,548	0.016	71.6	<0.0001	0.005	61	<0.0001	0.003	74.5	<0.0001	0.076	57.5	<0.0001	0.0033	76.7	<0.0001
>7 points	18	9,373	11,230	0.33	78.9	<0.0001	0.205	82	<0.0001	0.143	85.3	<0.0001	0.183	67.5	<0.0001	0.158	87	<0.0001
Cancer Type
OSCC	2	674	721	<0.001	0	0.377	<0.001	3.9	0.308	<0.001	33	0.222	0.004	0	0.57	<0.001	6.9	0.3
CRC	5	2,777	4,409	1.000	85	<0.0001	0.849	68.3	0.013	0.96	81.4	<0.0001	1.000	82.1	<0.0001	0.93	84.4	<0.0001
BC	4	1,788	1,955	0.884	60.8	0.054	1.000	88.4	<0.0001	0.865	87.1	<0.0001	1.000	11.3	0.336	0.966	85.7	<0.0001
GC	2	583	549	1.000	84.4	<0.0001	0.996	90.3	<0.0001	1.000	91.4	<0.0001	1.000	80.9	0.022	1.000	91.6	<0.0001
HCC	3	961	2,530	0.149	92.2	<0.0001	0.285	82.4	0.003	0.53	89.9	<0.0001	0.137	85.5	<0.0001	0.19	89.8	<0.0001
PC	4	2,207	2,358	0.185	57.6	0.07	0.447	70	0.019	0.221	78.2	0.003	0.25	9.6	0.345	0.248	69.5	0.02
OC	4	1,463	1,573	<0.001	0	0.462	0.005	51.6	0.102	<0.001	39.8	0.173	0.0012	0	0.416	<0.001	38.5	0.181
LC	5	2,793	2,921	0.23	69.1	0.012	0.368	86.3	<0.0001	0.378	86.9	<0.0001	0.04	12	0.337	0.41	83.2	<0.0001
NPC	3	1,573	2,182	0.0038	0	0.504	<0.001	0	0.728	<0.001	0	0.561	0.067	0	0.633	<0.001	0	0.426
RCC	2	1,356	1,895	1.000	1.9	0.313	0.973	34.2	0.218	1.000	0	0.583	1.000	53.6	0.142	1.000	0	0.945
Other cancers	8	1,867	3,685	0.962	71.8	0.001	0.500	53.2	0.046	0.768	76.4	0.002	0.691	56.4	0.025	0.78	77.6	<0.0001

P values in bold denotes significance.

^aP Values were corrected to adjust for multiple testing.

^bThe value of I² statistics for heterogeneity test.

^cP value of the Q-test for heterogeneity test.