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. 2016 Jul 22;6:30329. doi: 10.1038/srep30329

Table 3. Mortality according to the number of metabolic diseases.

  All-cause mortality Cardiovascular mortality Cancer mortality Other-cause mortality
Total subjects
 0 (n = 225984) 1 (ref) 1 (ref) 1 (ref) 1 (ref)
 1 (n = 79768) 1.18 (1.12, 1.25) 1.80 (1.58, 2.05) 1.07 (0.98, 1.16) 1.12 (1.04, 1.21)
 2 (n = 15838) 1.36 (1.26, 1.47) 2.09 (1.74, 2.51) 1.11 (0.97, 1.26) 1.40 (1.24, 1.58)
 3 (n = 1585) 1.77 (1.44, 2.16) 3.66 (2.48, 5.41) 0.87 (0.57, 1.34) 2.09 (1.58, 2.78)
P for trend <0.001 <0.001 0.130 <0.001
Body mass index <25 kg/m2
 0 (n = 172681) 1 (ref) 1 (ref) 1 (ref) 1 (ref)
 1 (n = 47591) 1.21 (1.14, 1.29) 1.76 (1.52, 2.05) 1.10 (0.99, 1.20) 1.16 (1.06, 1.27)
 2 (n = 7770) 1.45 (1.31, 1.59) 2.00 (1.60, 2.50) 1.17 (0.99, 1.38) 1.54 (1.34, 1.77)
 3 (n = 664) 2.34 (1.84, 2.97) 4.84 (3.08, 7.61) 1.29 (0.78, 2.11) 2.57 (1.82, 3.63)
P for trend <0.001 <0.001 0.011 <0.001
Body mass index ≥25 kg/m2
 0 (n = 53303) 1 (ref) 1 (ref) 1 (ref) 1 (ref)
 1 (n = 32177) 1.20 (1.08, 1.34) 2.11 (1.59, 2.81) 1.05 (0.89, 1.23) 1.13 (0.96, 1.34)
 2 (n = 8068) 1.38 (1.19, 1.59) 2.70 (1.91, 3.82) 1.08 (0.86, 1.36) 1.35 (1.08, 1.70)
 3 (n = 921) 1.29 (0.89, 1.87) 2.68 (1.23, 5.84) 0.47 (0.19, 1.14) 1.85 (1.13, 3.02)
P for trend <0.001 <0.001 0.991 0.001

Data are expressed as the HR (95% confidence interval).

Adjusted for age, sex, smoking, alcohol drinking, exercise, and income.