Table 1. Nanoparticle characterization: Hydrodynamic diameter and zeta potential of non-PEGylated NP and PEGylated NP, mean ± standard error of mean (n = 3).
| Nominal NP size (nm) |
Hydrodynamic Diameter (nm) of NP |
Zeta Potential (mV) of NP |
||
|---|---|---|---|---|
| non-PEGylated | PEGylated | non-PEGylated | PEGylated | |
| 20 | 19.6 ± 2.0 | 24.7 ± 2.0 | −44.1 ± 3.3 | −28.4 ± 3.2* |
| 40 | 50.1 ± 3.5 | 58.4 ± 4.0 | −46.0 ± 3.5 | −9.2 ± 4.0* |
| 100 | 91.5 ± 5.4 | 101.9 ± 6.0 | −55.3 ± 3.1 | −22.4 ± 3.5* |
| 500 | 507.0 ± 27.5 | 517.6 ± 34.8 | −57.9 ± 1.5 | −26.5 ± 2.0* |
*p < 0.05, t-test. Measurements in 20 mM HEPES (pH 7.4).