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. 2016 Jul 22;6:29820. doi: 10.1038/srep29820

Figure 3. The synthetic route of compound ZYZ-488.

Figure 3

. (a) CHCl3, TBAB, K2CO3, 12 h; (b) CH2Cl2, TFA, r.t., 12 h; (c) CH2Cl2/CH3OH (1:9), guadine, 0 °C, 2 h.