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. 2016 Jul 22;6:29820. doi: 10.1038/srep29820

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Copyright © 2016, Macmillan Publishers Limited

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(A) Effects of different dosed ZYZ-488 and LEO on cell viability in hypoxia-induced H9c2 rat ventricular cells. (B) Effects of ZYZ-488, LEO on LDH leakage in hypoxia-induced H9c2 rat ventricular cells. (C) Effects of ZYZ-488, LEO on CK activity in hypoxia-induced H9c2 rat ventricular cells. H9c2 cells were treated with ZYZ-488, LEO in hypoxia for 12 h. ^#P < 0.05; ^##P < 0.01; ^###P < 0.001 versus control group. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001 versus vehicle group. ^$$P < 0.01 versus LEO 10 μM treatment group. Error bars represent the data obtained from the experiments repeated three times or more.