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. 2016 Jul 22;6:29820. doi: 10.1038/srep29820

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(A) Apoptosis fraction of hypoxia-induced H9c2 rat ventricular cells with or without ZYZ-488 and LEO was measured by AnnexinV-FITC/PI assay. (B) Percentage of apoptotic cardiomyocytes under the treatment of ZYZ-488 and LEO was then analyzed based on AnnexinV-FITC/PI stain. ^###P < 0.001 versus control group. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001 versus vehicle group. ^$P < 0.01 versus LEO 10 μM treatment group.