Table 2.

Study inclusion and exclusion criteria

Inclusion criteria
	Documented diagnosis of granulomatosis with polyangiitis (Wegener’s), microscopic polyangiitis or renal limited vasculitis according to Chapel Hill Consensus Conference Criteria
	In stable remission (no documented clinical disease activity) for at least 6 months prior to study entry
	On maintenance immunosuppression with prednisolone, mycophenolate mofetil or azathioprine alone or in combination (maximum two agents)
	Documented past evidence (any time point) of CMV infection (CMV-specific immunoglobulin G detected in peripheral blood)
	Documentation that female patients of child-bearing potential are not pregnant and are using an appropriate form of contraception
	Written informed consent for study participation
Exclusion criteria
	Stage 5 CKD (estimated glomerular filtration rate (eGFR) <15 ml minute-1 1.73 m-2); tests performed within 6 months of pre-baseline visit can be used for this assessment
	Other significant chronic infection (HIV, hepatitis B, hepatitis C or tuberculosis)
	B-cell depleting therapy within 12 months or T-cell depleting therapy within 6 months
	Treatment with anti-CMV therapies in the last month
	Underlying medical conditions, which in the opinion of the investigator place the patient at unacceptably high risk for participating in the study
	Inability to participate fully or appropriately in the study