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. 2016 Jul 22;14:189. doi: 10.1186/s12957-016-0946-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Kaplan-Meier survival plot of 62 colorectal cancers with advanced stage UICC III/IV (all treated with 5-FU-based chemotherapy) in relation to nuclear Beclin-1 immunoexpression. In this subgroup, strong Beclin-1 expression was significantly associated with decreased OS survival (log-rank test: p = 0.011)