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. 2016 Jul 22;14:189. doi: 10.1186/s12957-016-0946-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — LC3 immunohistochemistry. On the left side, there is a cancer without any dot-like LC3 immunostaining. Notice the positively stained nerve, which can be considered as a positive internal control, since nerve fibers are constantly LC3 positive. On the right side, there is a CRC with a strong and characteristic dot-like LC3 immunostaining. A diffuse cytoplasmic staining was not noticed (×400 magnification)