Table 2.

Univariate analysis (Kaplan-Meier, log-rank test) for prognostic significance of p62, histological grading, lymph node and distant metastases and tumour stage in relation to tumour-specific overall survival in the complete cohort

Parameter	p value
Cytoplasmic p62 (negative/positive)	0.043*
Cytoplasmic Beclin-1 expression (positive/negative)	0.464
Nuclear Beclin-1 expression (positive/negative)	0.106
Histological grading (G1-G3)	0.032*
Lymph node metastases (pN0 vs pN+)	<0.001*
Tumour stage (pT1-4)	<0.001*
Distant metastases (M0 vs M1)	<0.001*

*Statistically signifcant