Table 3A.
A. Clinical characteristics of optic neuritis cases associated or not with anti-TNFα in IBD patients [n = 12].
| Visual field | Superior and temporal defect | Altitudinal defect | Ukn | Altitudinal defect | Ukn | No | No | Temporal defect | Ukn | Altitudinal defect | Central defect | Ukn |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Initial VA RAPD/VEP |
6/10 Positive/PL |
Finger count / positive/PL | 5/10 ND/ND |
ND positive/PL |
3/10 ND/ND |
4/10 ND/PL |
5/10 ND/ND |
5/10–6/10 ND/PL |
4/10 ND/ND |
5/10 positive/U |
6/10 ND/ND |
Ukn ND/PL |
| Symptoms | Blurred vision, pain, dyschromatopsia | Blurred vision, dyschromatopsia | Blurred vision, discomfort | Blurred | No | Ukn | Blurred vision, pain, phosphenes | Blurred vision, pain, phosphenes, dyschromatopsia | Blurred vision | Blurred vision | Blurred vision | Blurred vision, pain, phosphenes, diplopia |
| Time interval since last anti- TNF administration [days] | Ukn | 6 | No anti-TNFα | Ukn | Ukn | 30 | 44 | 60 | 17 | No anti-TNFα | 90 | 1 |
| Onset [days] | 3 | 5 | 7 | Ukn | Ukn | 14 | 18 | 7 | 1 | Few | 3 | Acute |
| Ocular involvement | MR | MR | MR | MA | MR | MR | MA | BR | MA | MA | MR | MUkn |
| Sex/age [years] | M/37 | F/46 | F/31 | F/42 | M/41 | F/36 | F/31 | F/47 | F/58 | M/50 | F/29 | F/30 |
| Cases | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
BR, bilateral retrobulbar; F, female; IBD, inflammatory bowel disease; M, male; MA, monocular anterior; MR, monocular retrobulbar; MUkn, monocular unknown; ND, not done; PL, prolonged latency; RAPD, relative afferent pupillary defect; TNF, tuour necrosis factor; Ukn, unknown; VA, visual acuity; VEP, visual evoked potential.