Figure 1.

Differences in bone microarchitecture in inflammatory bowel disease [IBD] patients. [A] Changes of total bone mineral density, trabecular bone volume, cortical thickness and cortical porosity between Crohn’s disease, ulcerative colitis, and controls. [B] Patients with inflammatory bowel disease [IBD, Crohn’s disease, ulcerative colitis] were divided into three groups according to previous administration of high-dose therapy [≥ 5mg prednisone equivalent daily] exceeding 3 months in pulse treatment and long-term treatment: group I, 0–3 pulses; group II, 4–10 pulses; group III, more than 10 pulses or continuous treatment for at least 1 year. Ct, cortical; BMD, bone mineral density; BV/TV, bone volume over total volume, N.S. = not significant; *p < 0.05; **p < 0.001.