Table 2.

Diagnostic delays [months] in patients with CD [n = 478], UC [n = 682], and IC [n = 36].

	Diagnosis	Univariable analysis			Multivariable analysis
		OR	95% CI	p-Value	OR	95% CI	p-Value
Sex, male/female
	UC	1.21	0.85–1.71	0.29
	CD	1.07	0.71–1.62	0.75
Ethnic group, Romanian/other
	UC	0.93	0.54–1.52	0.77
	CD	1.35	0.77–2.32	0.28
Age at diagnosis, under/over 40 years
	UC	0.7	0.49–0.99	0.04	0.68	0.48–0.97	0.04
	CD	0.93	0.59–1.44	0.75
Disease location
Proctitis versus extended [UC]	UC	1	0.64–1.53	1
L1 versus [L2 + L3] [CD]	CD	0.54	0.33–0.91	0.02	0.5	0.27–0.95	0.03
L1 versus L2 [CD]	CD	0.46	0.26–0.81	0.007
Perianal disease, absent/present	CD	1.44	0.782.6	0.23
EIM, absent/present
	UC	1.28	0.72–2.2	0.38
	CD	1.14	0.69–1.85	0.59
Past history of appendectomy, absent/present
	UC	1.64	0.77–3.32	0.18	1.78	0.83–3.63	0.12
	CD	1.33	0.79–2.2	0.27
Provenance, urban/rural
	UC	1.17	0.8–1.7	0.47
	CD	0.65	0.38–1.09	0.14	0.68	0.34–1.3	0.26
Smoking status
Non-smoker/smoker
	UC	0.99	0.62–1.54	0.95
	CD	1.58	1–2.48	0.05	2.09	1.19–3.68	0.01
Non-smoker/unknown
	UC	0.75	0.35–1.48	0.43
	CD	1.46	0.7–2.89	0.29	2.1	0.8–5.23	0.12
Onset of symptoms in summer, no/yes
	UC	1.19	0.78–1.78	0.41
	CD	3.32	2.01–5.53	< 0.001	3.35	1.99–5.69	0.000
Family history of IBD, negative/positive
	UC	0.38	0.06–1.34	0.19	0.38	0.06–1.38	0.21
	CD	0.68	0.15–2.16	0.55
Region
Transylvania/Banat
	UC	1.06	0.5–2.11	0.87
	CD	0.51	0.2–1.21	0.14	0.64	0.23–1.76	0.39
Transylvania/Moldova
	UC	0.91	0.54–1.5	0.72
	CD	0.47	0.17–1.2	0.13	0.6	0.2–1.72	0.35
Transylvania/ Muntenia	UC	1.08	0.72–1.6	0.72
	CD	0.88	0.5–1.62	0.68	1.04	0.51–2.2	0.92
History of autoimmune diseases, no/yes
	UC	1.02	0.22–3.47	0.98
	CD	1.52	0.56–3.75	0.38
History of diabetes mellitus, no/yes
	UC	0.6	0.17–1.62	0.36
	CD	0.81	0.18–2.64	0.75

Bolded binary outcomes denote the reference values for the odds ratio.

CD, Crohn’s disease; UC, ulcerative colitis; EIM, extraintestinal manifestations; IBD, inflammatory bowel disease; OR, odds ratio; CI, confidence interval.