Table 1.
Demographic characteristics (Knee-based data: N=196 knees)
| Baseline data | |||
|---|---|---|---|
| Age (years): Mean (standard deviation) | 59.8 (6.3) | ||
|
| |||
| BMI (kg/m-2): Mean (standard deviation) | 29.5 (4.6) | ||
|
| |||
| Sex | Female: n (%) | 122 (62.2) | |
| Male: n (%) | 74 (37.8) | ||
|
| |||
| Clinical site | Alabama: n (%) | 108 (55.1) | |
| Iowa: n (%) | 88 (44.9) | ||
|
| |||
| Malalignment | Varus (<179°): n (%) | 86 (43.9) | |
| Neutral (179-181°): n (%) | 73 (37.2) | ||
| Valgus (>181°): n (%) | 37 (18.9) | ||
|
| |||
| Kellgren and Lawrence grade | 0 | 108 (55.1) | |
| 1 | 42 (21.4) | ||
| 2 | 25 (12.8) | ||
| 3 | 18 (9.2) | ||
| 4 | 3 (1.5) | ||
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| |||
| Longitudinal data | |||
|
| |||
| Change in lateral tibial and femoral mean cartilage thickness (μm) | -25.10 (140.54) | ||
|
| |||
| Change in medial tibial and femoral mean cartilage thickness (μm) | -63.01 (184.11) | ||