Table 3.

Prognostic value of semiquantitative MRI-based risk factors in the lateral TF compartment

Risk factor at baseline	Non-progressors (N=167) n (%)	Progressors: cartilage thickness decrease >147 μm (N=29) n (%)	aOR (95% CI)	P-value
Meniscal damage WORMS score ≥1 *	7 4.29	8 27.59	12.16*** (2.64, 56.00)	0.0013
Meniscal extrusion (present)**	10 6.17	7 24.14	1.43*** (0.52, 3.92)	0.4889
Cartilage WORMS score ≥2*	74 45.40	21 72.41	3.08*** (1.14, 8.29)	0.0259
BML WORMS score ≥1 *	40 24.54	10 34.48	1.46*** (0.50, 4.21)	0.4865
Effusion synovitis WORMS score ≥1 *	116 71.17	19 65.52	1.43*** (0.52, 3.92)	0.4889
Hoffa synovitis WORMS score ≥1 *	95 58.28	16 55.17	0.74*** (0.29, 1.86)	0.5198
Radiographic OA (KL grade ≥2)	5 2.99	7 24.14	8.50**** (1.97, 36.63)	0.0041

^*4 subjects had missing WORMS reading for this feature and were excluded from analysis

^**5 subjects had missing WORMS reading for this feature and were excluded from analysis

^***Adjusted for age, BMI, gender, clinic site, alignment and KL grade

^****Adjusted for age, BMI, gender, clinic site, and alignment