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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Curr Pharmacol Rep. 2016 Mar 11;2(3):113–128. doi: 10.1007/s40495-016-0055-0

Figure 3. VO representation of vaccine knowledge.

Figure 3

This example ontologically represents the information about Afluria, a killed inactivated influenza vaccine manufactured by the company CSL Limited. In addition to the inactivated influenza virus, the vaccine contains chicken egg protein allergen. The vaccine is administered to humans through intramuscular route. The human’s background such as age can be linked to the vaccination event. The Afluria vaccination has the ability of inducing specific adaptive immunity against virulent influenza infection as well as various adverse events. Note that the AEs that are known to be induced by specific vaccines are primarily represented in OVAE instead of VO.