Fig. 1.

Schematic of analytical approaches which can be applied on rsfMRI data. The connectivity domain, similar to the time domain, allows us to perform a wide range of data-driven methods. The connectivity domain also supports implementing model-based methods such as first-level generalized linear model (GLM) on rsfMRI data (blue box). While feature-based approaches have been performed as second-level analyses, the connectivity domain provides us the opportunity to perform feature-based techniques at both first and second levels.