Fig. 8.

Demonstration of advantages of connectivity domain over time domain. For all results presented for both the time and connectivity domain in this figure, the two methods compared are different first-level analytical techniques that produce spatial maps for each individual subject. The spatial map for each component was averaged across subjects for each method and the spatial similarity between these average maps is reported here as a percentage. (a) Demonstrates the superiority of the connectivity domain for performing TC-BR analyses by comparing the spatial similarity of spatial maps (IC maps) generated with Infomax and FastICA in the time and connectivity domains. (b) Demonstrates the compatibility of model-based methods, such as GLM, with the connectivity domain by assessing the spatial similarity of output maps generated in the connectivity domain using TC-BR and GLM (design matrix 1: design matrix computed from session 1 data), which show good agreement. (c) Demonstrates the consistency of a design matrix over time by assessing the spatial similarity between GLM output maps generated using the 1^st session data and the design matrix from the same session as compared to the design matrix generated from the other session (design matrix 2: design matrix computed from session 2 data).