Table 1.
Investigation results
| Test (reference range) | Initial hospital presentation | Admission to our hospital | First discharge | Second hospital presentation | Second discharge |
|---|---|---|---|---|---|
| Haemoglobin (115–160 g/L) | 70 | 72 | 103 | 81 | 109 |
| Platelets (150–400 × 109/L) | 17 | 30 | 351 | 8 | 314 |
| Film | Not performed | Moderate polychromasia, fragmented red cells and spherocytes | Occasional spherocyte and fragmented red cell noted | Moderate numbers of fragmented red cells and spherocytes, large platelets |
Occasional red cell fragment |
| Direct Coombs test | Not performed | Negative | Negative | Negative | Not performed |
| LDH (150–280 U/L) | 839 | 970 | 206 | 1630 | 328 |
| Bilirubin (<20 µmol/L) | 35 | 34 | 6 | 51 | 9 |
| Haptoglobin (0.36–1.95 g/L) | Not performed | 0.02 | 2.06 | 0.03 | 0.82 |
| Creatinine (46–90 mmol/L) | 90 | 95 | 61 | 118 | 77 |
| eGFR (>90 mL/min/1.73 m2) | 75 | 70 | >90 | 54 | >90 |
| ADAMTS13 activity | >94% | 102% (after 2 units PRBC and 2 units FFP) | Not performed | 146% | N/A |