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. 2016 Jul 22;16:107. doi: 10.1186/s12887-016-0641-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Performance assessment (sensitivity and specificity) plots for NP-C cases versus NP-C non-cases and controls. High sensitivity and specificity was achieved with NP-C cases versus NP-C non-cases or controls, and aided the assignment of cut-off scores (vertical dashed lines) for low (<3), moderate (3–5) and high (≥6) likelihood