Table 2.

Predictors of Administration of Adjuvant Mitotane: Binary Logistic Regression

Variable	Univariate			Multivariable
	OR	95% CI	p Value	OR	95% CI	p Value
Male	1.1	0.6–1.9	0.78
Age, y	1.0	1.0–1.0	0.10
BMI, kg/m2	1.0	0.9–1.0	0.34
ASA class
1	1.0	Ref	Ref
2	1.1	0.4–2.9	0.89
3	1.0	0.4–2.4	0.97
4	0.6	0.1–2.3	0.43
Hormone secretion	2.9	1.6–5.3	<0.001	2.4	1.3–4.5	0.01*
Familial syndrome	1.5	0.2–10.6	0.71
Minimally invasive procedure	1.0	0.5–2.0	0.93
Additional organ resection	1.7	1.0–3.1	0.06
Intraoperative tumor rupture	1.0	0.4–2.6	0.97
Tumor size, cm	1.0	1.0–1.1	0.24
Stage
I	1.0	Ref	Ref	1.0	Ref	Ref
II	2.4	0.5–12.2	0.29	2.2	0.4–11.7	0.35
III	3.1	0.6–15.6	0.17	2.7	0.5–14.4	0.24
IV	6.3	1.3–31.7	0.03	4.8	0.9–25.3	0.07
R0	1.0	Ref	Ref
R1	1.4	0.7–2.8	0.30
R2	1.0	0.3–3.7	0.99
Complication	1.3	0.7–2.5	0.35

^*Significant.

ASA, American Society of Anesthesiologists; BMI, body mass index; OR, odds ratio; R0, microscopically negative margin; R1, microscopically positive margin; R2, grossly positive margin; Ref, reference.