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KPV does not reduce tumorigenesis in a genetic model of intestinal cancer. APCMin/+ were treated or not with KPV diluted at a concentration of 100 μmol/L in drinking water. (A) Number of small intestinal adenomas per mouse. (B) Number of colonic adenomas per mouse. (C) Tumor size distribution. (D) Spleen weight and (E) colon length. (F) Lipocalin-2 (LCN-2) was measured in feces collected from 5-week-old, 11-week-old, and 18-week-old mice. Values are means ± SEM (n = 5–6 per group).
