Table 4.

Characteristics of three patients who had high ORS but low RS using our formula

		Patient #1	Patient #2	Patient #3
Age		63	67	63
Surgery		Excision ALD	Excision ALD	Excision
ORS		35	34	38
RS using our formula		15.57	17.6	15.2
ER	IHC (Allred score)	8	6	8
	RT-PCR	Positive (8.5)*	Positive (11.1)	Positive (9.8)
PR	IHC (Allred score)	6	4	0
	RT-PCR	Positive (5.7)	Negative (3.2)	Negative (3.2)
Tumor size (mm)		9	8	38
Node status positive/total (N-stage)		1/8 (1mi)	1/3 (1mi)	0/9
Histology		IC NST	IC NST	ILC
Nottingham grade		II	II	III
TIL		1	0	1
Necrosis		0	0	0
Therapy	Chemotherapy	Cytoxan/Taxotere	None**	Cytoxan/Taxotere
	Hormonal therapy	Arimidex	Arimidex	Arimidex
	Radiation therapy	Post excision	Post excision	Post excision
Survival		Alive and disease free (21 months)	Alive and disease free (24 months)	Bone metastases (28 months) Alive after 57 months

^*Interpretation (ER Negative < 6.5, Positive ≥ 6.5; PR Negative < 5.5, Positive ≥ 5.5);

^**Declined chemotherapy;

ALD, axillary lymph node dissection; mi, micrometastases (>0.2-mm and <2-mm); IC NST, invasive carcinoma no special type; ILC, invasive lobular carcinoma; TIL, tumor infiltrating lymphocytes