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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2016 Jan 22;138:81–89. doi: 10.1016/j.plefa.2016.01.001

Figure 3. RvD3 potently stops neutrophil recruitment and reduces proinflammatory cytokines, chemokines, and enzymes.

Figure 3

RvD3 (10 ng/mouse) or vehicle (saline) was administered i.v. 15 min prior to i.p. injection of zymosan (1 mg/mouse). Exudates were collected 4 hr later. (A and B) Cells were enumerated and PMN were identified using flow cytometry. (C–E) Pro-inflammatory cytokines, chemokines and enzymes were measured using the Proteome Profiler Mouse XL Cytokine Array Kit (R&D Systems). Results are mean ± SEM, n=3–4 mice per group. *P < 0.05, **P<0.01 versus zymosan plus vehicle.