FIG 3.

Time-kill kinetics against selected bacteria. The activity of the hit compounds against growths of H. influenzae (A) and E. faecalis (B) was determined. Compounds were added to bacterial cultures at 4× the MIC. Samples were analyzed by plating and determination of the CFU at 0, 2, 4, 6, and 24 h. Filled triangles (▲) represent cultures containing BM04E04, filled diamonds (◆) represent cultures containing BM03E08, and filled squares (■) represent cultures containing BM07F03. Filled circles (●) represent control cultures grown in the absence of compounds.