Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of CYP2B6 genotype on estimated effective and toxic concentrations of EFZ in plasma (a and b), EFZ in CSF (c and d), and total 8OH-EFZ in CSF (e and f). Error bars are geometric means and 95% confidence intervals for the GG/GT genotype and the geometric mean and range for the TT genotype. MTC, minimum toxic concentration; MEC, minimum effective concentration; ITC, in vitro toxic concentration.
