TABLE 2.

Proportion of CSF samples with EFZ and 8OH-EFZ concentrations above in vitro toxic concentrations^a

Drug and group	No. (%) of CSF samples from patients with the following CYP2B6 c.516G→T genotype:
	All	GG	GT	TT
EFZ
TBM	35 (76)	14 (61)	18 (90)	3 (100)
No TBM	3 (13)	0 (0)	2 (18)	1 (50)
8OH-EFZ
TBM	45 (98)	22 (96)	20 (100)	3 (100)
No TBM	20 (87)	10 (100)	9 (82)	1 (50)

^aIn vitro toxic concentrations are 31.6 ng/ml for EFZ and 3.3 ng/ml for 8OH-EFZ.