TABLE 1.
Demographic and clinical data for patients in this study
| Variablea | Mean value (SD)b |
P value | |||
|---|---|---|---|---|---|
| All patients (n = 19) | Nonobese patients (n = 6) | Obese patients (n = 7) | Morbidly obese patients (n = 6) | ||
| Age (yr) | 49 (15.9) | 41 (19.1) | 49 (16.2) | 58 (7.6) | 0.20 |
| Weight (kg) | 95 (22.0) | 71 (11.6) | 103 (6.8) | 109 (23.3) | <0.01 |
| Ideal body weight (kg) | 65 (12.9) | 65 (6.7) | 72 (6.3) | 55 (17.8) | 0.05 |
| Lean body weight (kg) | 60 (13.1) | 53 (7.3) | 70 (4.7) | 55 (17.7) | 0.03 |
| Height (cm) | 171 (12.2) | 173 (6.0) | 177 (7.0) | 162 (17.0) | 0.07 |
| Sex (male) | 11 (58) | 2 (33) | 7 (100) | 2 (33) | |
| BMI (kg/m2) | 33 (7.0) | 24 (3.4) | 33 (2.2) | 41 (1.4) | <0.01 |
| Scr (μmol/liter) | 72 (24.0) | 62 (26) | 89 (20.2) | 62 (16.2) | 0.05 |
| CG-TBW (ml/min) | 151 (62.6) | 139 (44.9) | 114 (39.3) | 206 (66.7) | 0.02 |
| CG-IBW (ml/min) | 100 (47.5) | 135 (59.9) | 80 (30.3) | 87 (34.2) | 0.07 |
| CG-LBW (ml/min) | 89 (33.5) | 107 (40.9) | 77 (27.9) | 86 (29.2) | 0.29 |
| Albumin level (g/liter) | 26 (6.1) | 24 (8.1) | 28 (5.1) | 24 (4.8) | 0.40 |
| SOFA score | 6 (3.9) | 5 (2.8) | 6 (4.9) | 6 (3.8) | 0.80 |
| APACHE II score | 20 (6.9) | 26 (3.7) | 15 (4.2) | 20 (6.9) | <0.01 |
a
APACHE II, acute physiology and chronic health evaluation; BMI, body mass index; CLCR, measured creatinine clearance; CG-TBW, estimated CLCR calculated using Cockcroft-Gault equation based on total body weight; CG-IBW, estimated CLCR calculated using Cockcroft-Gault equation based on ideal body weight; CG-LBW, estimated CLCR calculated using Cockcroft-Gault equation based on lean body weight; Scr, serum creatinine; SOFA, sequential organ failure assessment.
b
Data on male gender are presented as numbers (%) of patients.