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Mean lung log10 CFU counts (±SD) (A to C) and change in lung CFU counts (week 4 − day 0) (D to F) after 4 weeks of treatment in mice infected with the parental H37Rv strain (A and D), the B5 mutant (B and E), or the complemented B5::pepQ strain (C and F). Abbreviations: UT, untreated; H, isoniazid (10 mg/kg); C, clofazimine (20 mg/kg); B, bedaquiline (25 mg/kg).
