. 2016 Jul 22;60(8):4809–4819. doi: 10.1128/AAC.00713-16

TABLE 1.

Susceptibilities of wild-type, IVM-selected, and MOX-selected C. elegans strains to IVM and MOX^d

Treatment	Mean EC₅₀ (nM) ± SD for wild-type Bristol N2 (no. of expts)	IVM-selected strain (IVR10)		MOX-selected strain
Treatment	Mean EC₅₀ (nM) ± SD for wild-type Bristol N2 (no. of expts)	Mean EC₅₀ (nM) ± SD (no. of expts)	RF	Mean EC₅₀ (nM) ± SD (no. of expts)	RF
IVM	1.69 ± 0.30 (9)	12.43 ± 1.65 (7)^a	7.34	12.46 ± 0.96 (8)^a	7.35
MOX	1.77 ± 0.25 (9)	3.06 ± 0.51 (11)^a,b,c	1.74	4.24 ± 0.58 (9)^a,b,c	2.39

P < 0.001 versus the wild type.

P < 0.001 versus IVM.

P < 0.001 for IVM-selected versus MOX-selected strains.

The EC₅₀ was calculated from LDA data. RF (resistance factor) is the fold resistance relative to Bristol N2, equal to the EC₅₀ for ML-selected strains/EC₅₀ for N2B. The ratios of the EC₅₀ of IVM to the EC₅₀ of MOX were 0.96 for the Bristol N2 strain, 4.03 for the IVM-selected strain, and 2.94 for the MOX-selected strain.