TABLE 2.
Susceptibilities of the wild-type Bristol N2, IVM-selected, and MOX-selected C. elegans strains to other anthelminticsa
Strain | Mean EC50 ± SD |
|||
---|---|---|---|---|
EPR (nM) | LEV (μM) | TCBZ So (μM) | ALB So (μM) | |
Wild-type Bristol N2 | 1.19 ± 0.61 | 16.63 ± 1.19 | 71.41 ± 1.57 | 6.72 ± 1.10 |
IVM-selected (IVR10) | 17.82 ± 1.87*** | 12.47 ± 1.12* | 38.7 ± 1.16*** | 7.97 ± 1.13 |
MOX-selected | 16.49 ± 1.37*** | 14.13 ± 1.23 | 39.87 ± 1.12*** | 8.81 ± 1.10 |
EC50 values were calculated from LDA data. *, P < 0.05; ***, P < 0.001 (versus the wild type) (n = 3).