TABLE 4.

Multilocus haplotypes in 21 participants with recurrences caused by Plasmodium vivax during 6 months

Sample identification no.	Time to first recurrence (days)f	Time to second recurrence (days)f	Day zero haplotype vs recurrence day haplotype	Haplotype code(s)e	Cluster no.	Pmatcha	Classificationb	Residence zone	Last episode of malaria before study (no. of mos.)	Travel to other region(s) of endemicity during follow-up	Family member with malaria at time of recurrence
1014	54		Identical	6	2	0.0019	Relapse	Rural	>12	No	No
1015	68	154	Identical	33c	2	0.5146	Reinfection	Rural	Never	No	No
1018	173		Identical	33	2	0.5146	Reinfection	Rural	7–12	No	No
1022	94		Identical	25	1	0.0008	Relapse	Rural	3–6	No	No
1034	103	170	Identical	39c	1	0.0019	Relapse	Urban	Never	Yes	No
1050	180		Identical	33	2	0.5146	Reinfection	Rural	1–2	Yes	No
1051	90		Identical	33	2	0.5146	Reinfection	Rural	Never	No	No
1052	81	154	Identical	48c	1	0.0019	Relapse	Rural	>12	Yes	No
1055	110		Identical	25	1	0.0008	Relapse	Urban	>12	Yes	No
1057	91		Identical	33	2	0.5146	Reinfection	Rural	Never	No	No
1063	108		Different	13 (day zero), 54 (R1)	1		Reinfection	Rural	>12	No	No
1065	72	142	Identical	3c	2	0.0572	Reinfection	Rural	>12	No	No
1066	80		Identical	28	2	0.0075	Relapse	Urban	Never	Yes	No
1075	179		Different	10 (day zero), 55 (R1)	1		Reinfection	Urban	1–2	Yes	No
1089	75	145	Identical	26c	1	0.0002	Relapse	Urban	1–2	No	No
1094	69		Identical	33	2	0.5146	Reinfection	Rural	3–6	No	No
1098	76		Identical	53	1	0.0002	Relapse	Rural	1–2	No	No
1101d	58	118	Identical	16c	1	0.0034	Relapse	Rural	>12	No	Yes
1102	99		Identical	16	1	0.0034	Relapse	Rural	Never	No	No
1103	57	177	Identical	16c	1	0.0034	Relapse	Rural	Never	No	Yes
1111	51		Identical	17	1	0.0002	Relapse	Urban	1–2	No	No

^aProbability of finding by chance an identical haplotype in different episodes for a participant.

^bRelapse when P_match is less than 0.05 and reinfection when P_match is greater than or equal to 0.05.

^cSecond recurrence with haplotype identical to that of the previous two episodes in the study.

^dThird recurrence on day 179 with haplotype 16, identical to that of previous three episodes in the study.

^eR, recurrence number.

^fTime to recurrence is measure from day zero.