FIG 1.

Anti-M. avium activities of imidazo[1,2-a]pyridine-3-carboxyamides in vitro, as measured by CFU counts. M. avium was treated with compounds at various concentrations as shown, and then bacterial CFU were determined on Middlebrook 7H10 agar plates. Baseline, M. avium CFU at the beginning of treatment. The results are representative of the results from three independent experiments. *, P < 0.05 compared to the baseline (one-way analysis of variance [ANOVA] with Tukey posttest). Error bars indicate standard deviations from duplicate infections with or without drug treatment from a single experiment.