TABLE 2.

Microbiological features of representative Ureaplasma isolates of the study

Species and isolate no.	Specimen sourcea	MIC (μg/ml)b						tet(M)	QRDRc				MLST
		LEV	CIP	TET	DOX	ERY	AZM		gyrA	gyrB	parC	parE	ftsH	rpl22	valS	rprS	STd
U. parvum
IDRL-10860	Urine	4	16	≤0.125	≤0.125	0.5	0.5	−	WT	WT	S83L	WT	1	1	1	1	ST1
IDRL-10857	Vagina	4	16	0.5	0.25	2	2	−	WT	WT	S83L	WT	35	1	1	1	ST95
IDRL-10940	Vagina	8	16	≤0.125	≤0.125	0.5	0.5	−	WT	WT	S83L	WT	8	1	1	1	ST56
IDRL-10790	Urethra	4	16	≤0.125	≤0.125	0.5	0.5	−	WT	WT	S83L	WT	8	1	1	1	ST56
IDRL-10904	Cervix	4	16	8	2	0.5	0.5	+	WT	WT	S83L	WT	2	1	1	1	ST2
IDRL-11151	Cervix	4	16	≤0.125	≤0.125	0.5	0.5	−	WT	WT	S83L	WT	1	1	1	1	ST1
IDRL-11156	Urine	4	16	≤0.125	≤0.125	2	1	−	WT	WT	S83L	WT	8	1	1	1	ST56
IDRL-11160	Urine	16	>16	≤0.125	≤0.125	1	0.5	−	WT	WT	S83L	WT	2	1	22e	1	ST108f
IDRL-11170	Vagina	8	16	≤0.125	≤0.125	0.25	0.25	−	WT	WT	S83L	WT	1	2	1	1	ST22
IDRL-11178	Vagina	4	16	≤0.125	≤0.125	0.5	0.5	+	WT	WT	S83L	WT	1	1	1	1	ST1
IDRL-11211	Vagina	4	16	≤0.125	≤0.125	1	0.5	−	WT	WT	S83L	WT	1	1	23e	1	ST109f
IDRL-11260	Vagina	8	16	≤0.125	≤0.125	2	2	−	WT	WT	S83L	WT	1	12	1	1	ST103
IDRL-11232	Cervix	8	16	≤0.125	≤0.125	1	1	−	WT	WT	E87K	WT	20	2	1	1	ST111f
IDRL-11141	Vagina	0.5	2	0.25	≤0.125	1	1	+	ND	ND	ND	ND	2	2	1	2	ST105
IDRL-11142	Vagina	0.5	2	0.25	≤0.125	0.5	0.5	+	ND	ND	ND	ND	2	2	1	1	ST4
IDRL-11149	Urine	0.5	2	0.25	≤0.125	1	1	+	ND	ND	ND	ND	8	1	1	1	ST56
IDRL-11152	Cervix	0.5	2	0.25	≤0.125	0.5	0.5	+	ND	ND	ND	ND	2	2	1	1	ST4
IDRL-11177	Urine	0.5	2	≤0.125	≤0.125	0.5	0.5	+	ND	ND	ND	ND	8	1	1	1	ST56
IDRL-11179	Vagina	0.5	2	≤0.125	≤0.125	0.5	0.25	+	ND	ND	ND	ND	2	1	1	2	ST38
IDRL-11252	Vagina	0.25	0.5	≤0.125	≤0.125	0.25	0.25	+	ND	ND	ND	ND	2	14e	1	1	ST110f
IDRL-11268	Vagina	0.5	2	≤0.125	≤0.125	2	2	+	ND	ND	ND	ND	2	2	1	1	ST4
IDRL-10852	Vagina	0.25	2	≤0.125	≤0.125	2	2	−	ND	ND	ND	ND	2	2	1	1	ST4
IDRL-10835	Cervix	2	8	≤0.125	≤0.125	0.5	0.5	−	WT	WT	WT	WT	1	1	1	1	ST1
IDRL-10774	BAL	0.25	2	≤0.125	≤0.125	0.5	0.5	−	ND	ND	ND	ND	1	2	1	1	ST22
IDRL-10874	Vagina	0.5	2	≤0.125	≤0.125	0.5	0.25	−	ND	ND	ND	ND	1	1	1	1	ST1
IDRL-10923	Cervix	0.25	1	≤0.125	≤0.125	0.25	0.25	−	ND	ND	ND	ND	2	1	1	1	ST2
IDRL-11125	Cervix	0.25	2	≤0.125	≤0.125	1	1	−	ND	ND	ND	ND	2	14e	1	1	ST110f
IDRL-11207	Vagina	1	4	≤0.125	≤0.125	1	0.5	−	ND	ND	ND	ND	1	2	1	1	ST22
IDRL-11257	TA	0.5	2	≤0.125	≤0.125	0.25	0.25	−	ND	ND	ND	ND	1	1	1	1	ST1
IDRL-11271	Cervix	0.5	2	≤0.125	≤0.125	2	2	−	ND	ND	ND	ND	2	1	1	1	ST2
U. urealyticum
IDRL-10763	BAL	4	16	0.25	≤0.125	2	2	−	WT	WT	S83L	WT	5	3	4	5	ST7
IDRL-11217	Urine	4	16	0.25	≤0.125	2	2	−	WT	WT	WT	WT	5	3	4	4	ST47
IDRL-10967	Vagina	2	8	0.5	≤0.125	2	2	−	WT	WT	WT	WT	5	3	4	4	ST47
IDRL-11184	Vagina	2	8	0.5	≤0.125	2	2	−	WT	WT	WT	WT	5	3	4	4	ST47
IDRL-11235	TA	0.5	4	0.25	≤0.125	2	2	−	ND	ND	ND	ND	42e	3	4	18e	ST112f
IDRL-11135	Urine	1	4	0.5	≤0.125	2	2	−	ND	ND	ND	ND	6	3	4	11	ST54
IDRL-10787	Cervix	2	8	0.25	≤0.125	1	1	−	ND	ND	ND	ND	5	3	4	4	ST47
IDRL-10928	Urine	0.5	2	0.25	≤0.125	0.25	0.25	−	ND	ND	ND	ND	4	11	4	4	ST113f
IDRL-11163	Cervix	0.5	4	≤0.125	≤0.125	1	1	−	ND	ND	ND	ND	4	3	4	4	ST9
IDRL-11213	Vagina	0.5	4	0.25	≤0.125	2	2	−	ND	ND	ND	ND	41	3	4	11	ST101
IDRL-11269	Cervix	0.5	2	0.5	≤0.125	2	2	−	ND	ND	ND	ND	6	3	4	11	ST54
IDRL-11295	Urine	0.5	2	≤0.125	≤0.125	1	1	−	ND	ND	ND	ND	42e	3	4	18e	ST112f
IDRL-11298	Urine	0.5	2	≤0.125	≤0.125	2	1	−	ND	ND	ND	ND	5	3	4	4	ST47
IDRL-11299	Urine	0.5	2	≤0.125	≤0.125	1	0.5	−	ND	ND	ND	ND	4	3	4	4	ST9
IDRL-11306	Urine	0.5	2	≤0.125	≤0.125	1	0.5	−	ND	ND	ND	ND	5	3	4	5	ST7
IDRL-11308	Urine	2	8	0.25	≤0.125	1	0.5	−	ND	ND	ND	ND	4	3	4	4	ST9

^aBAL, bronchoalveolar lavage fluid; TA, tracheal aspirate.

^bLEV, levofloxacin; CIP, ciprofloxacin; TET, tetracycline; DOX, doxycycline; ERY, erythromycin; AZM, azithromycin.

^cWT, wild type; ND, not done.

^dST, sequence type.

^eNew alleles; numbering starts from the last alleles reported by Zhang et al. (17) and Schneider et al. (9).

^fNew STs; numbering starts from the last profiles reported by Zhang et al. (17) and Schneider et al. (9).