TABLE 2.

MICs of A. baumannii strains in the absence and presence of PF-5081090

Strain	EUa fold change	MIC (mg/liter) ofb:
		AMK		AZM		CIP		CST		IPM		RIF		TGC		VAN		In
		−In	+In	−In	+In	−In	+In	−In	+In	−In	+In	−In	+In	−In	+In	−In	+In
ATCC 19606	8.4	2	1	0.5	0.125	0.125	0.125	0.125	2	1	0.25	2	≤0.03	0.06	0.125	128	8	256
Ab-84	7.4	8	2	64	64	128	128	0.06	0.25	128	64	2	≤0.03	0.5	0.5	128	16	256
Ab-108	5.5	256	64	16	2	32	32	0.06	0.5	256	64	2	≤0.03	0.5	0.5	128	16	256
Ab-167	6.5	256	64	16	2	64	64	0.125	2	256	64	4	≤0.03	1	0.5	128	16	256
Ab-176	3.5	256	64	16	2	64	64	0.25	0.5	256	64	4	≤0.03	0.5	0.5	128	16	256
Ab-7	NDc	16	8	64	4	64	64	0.125	1	16	4	32	≤0.03	0.5	0.5	256	32	256
Ab-31	ND	64	8	16	1	32	32	0.125	2	32	4	32	≤0.03	0.25	0.25	256	16	256

^aEU, endotoxic units.

^bAMK, amikacin; AZM, azithromycin; CIP, ciprofloxacin; CST, colistin; In, PF-5081090; IPM, imipenem; RIF, rifampin; TGC, tigecycline; VAN, vancomycin; −In, absence of 32 mg/liter of PF-5081090; +In, presence of 32 mg/liter of PF-5081090.

^cND, not determined.