FIG 1.

Direct effect of aspirin and ibuprofen on macrophage (MØ) growth (A) and the corresponding expression of this effect as the percent reduction in growth (B). Analysis of the data revealed that aspirin at 180 μg/ml (1 mM) effected only an 11% reduction in growth, while ibuprofen at 206 μg/ml (1 mM) effected a 13% reduction. The findings suggest that aspirin and ibuprofen are nontoxic to macrophages at the tested concentrations, as they did not yield a 50% reduction in growth. Ethanol (EToH) and DMSO were included as controls. ASA, acetylsalicylic acid (aspirin); IBU, ibuprofen.