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Hepatic profiles of LPC, PG, FFA, Cer, HexCer and SM in the LDLR knockout rats. Lipids were extracted from the liver, and LPC (A), PG (B), FFA (C), Cer (D), HexCer (E) and SM (G) species were determined via LC-MS. The levels of each lipid species in the wild-type rats were set to one, and their levels in the LDLR knockout rats were normalized against the respective wild-type values. The data are given as the mean±s.e.m., *P<0.05. WT: n=7; KO: n=5.
