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. 2016 Jul 10;2016:3026563. doi: 10.1155/2016/3026563

Table 3.

Pathological diagnosis on biopsy of normal upper GI tract and cost per positive finding.

Pathological finding Abnormal histology (%) (absolute number) Cost/positive finding ($ CAD)
Esophagus
Reflux esophagitis 16% (81/502) $489
Eosinophilic esophagitis 3% (13/502) $2963
Barrett's esophagus 1% (4/502) $8889

Stomach
Chronic gastritis 23% (243/1054) $351
Chronic gastritis with IM 4% (42/1054) $2282
HP gastritis 6% (62/1054) $1404
HP gastritis with IM 1% (12/1054) $6086
Reactive gastropathy 7% (69/1054) $1217
Reactive changes 1% (15/1054) $6086

Duodenum
Increased IEL 6% (54/918) $450
Duodenitis 2% (22/918) $3501
Celiac disease 3% (25/918) $3024
Lymphoid hyperplasia 0.5% (5/918) $16631

IM = intestinal metaplasia, HP = Helicobacter pylori, and IEL = intraepithelial lymphocytes.

The percentages expressed in this table identify the yield of the diagnosis in patients with macroscopically normal EGDs that were biopsied.