Table 5.
Yield of pathologic abnormality and cost per positive finding on macroscopically normal EGDs based on the clinical indication.
| Indication | Pathologic finding | Histologic abnormality (%) (absolute number) |
Cost/positive finding ($ CAD) |
|---|---|---|---|
| Dysphagia | Reflux esophagitis | 25% (14/56) | $313 |
| Eosinophilic esophagitis | 11% (6/56) | $711 | |
|
| |||
| Heartburn | Reflux esophagitis | 21% (24/113) | $372 |
| Eosinophilic esophagitis | 0% (0/113) | — | |
|
| |||
| Dyspepsia | Reflux esophagitis | 15% (33/220) | $521 |
| Chronic gastritis | 27% (140/520) | $298 | |
| HP gastritis | 6% (31/520) | $1404 | |
| Celiac disease | 2% (8/420) | $3992 | |
|
| |||
| Anemia | Reflux esophagitis | 0% (0/7) | — |
| Chronic gastritis | 30% (29/97) | $268 | |
| HP gastritis | 15% (15/97) | $536 | |
| Duodenitis | 1% (2/151) | $7983 | |
| Increased IEL | 7% (11/151) | $1140 | |
| Celiac disease | 1% (2/151) | $7983 | |
|
| |||
| Diarrhea | Increased IEL | 7% (6/91) | $1140 |
| Celiac disease | 6% (5/91) | $1331 | |
|
| |||
| Nausea and vomiting | Reflux esophagitis | 7% (3/41) | $1117 |
| Eosinophilic esophagitis | 2% (1/41) | $3911 | |
| Chronic gastritis | 24% (20/85) | $335 | |
| HP gastritis | 6% (5/85) | $1404 | |
|
| |||
| GI bleed | Reflux esophagitis | 0% (0/2) | — |
| Chronic gastritis | 27% (8/30) | $298 | |
| HP gastritis | 10% (3/30) | $803 | |
| Duodenitis | 5% (1/21) | $1597 | |
The percentages in this table indicate the yield of an abnormality found on a macroscopically normal EGD with a targeted indication.