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. Author manuscript; available in PMC: 2016 Jul 24.
Published in final edited form as: Genet Epidemiol. 2015 Oct 23;39(8):635–650. doi: 10.1002/gepi.21930

Table IV.

Power comparison for two binary traits. p : allele frequency at the QTL, m : allele frequency at the marker locus. Penetrance vectors (f0,f1,f2) for the disease 1 and 2 are presented in consecutive rows.

p=0.2,m=0.2 p=0.1,m=0.2

LD Penetrances MultiPhen BAMP DAMP Penetrances MultiPhen BAMP DAMP
O(TIerror) both recessive 0.051 0.052 0.052 both additive 0.052 0.051 0.051
0.33 (0.25, 0.08, 0.08) 0.19 0.23 0.24 (0.12,0.08,0.04) 0.15 0.15 0.17
0.66 (0.25, 0.08, 0.08) 0.52 0.69 0.71 (0.12,0.08,0.04) 0.47 0.47 0.50
0.95 0.75 0.93 0.93 0.78 0.78 0.80
p=0.1,m=0.3 p=0.1,m=0.2

LD Penetrances MultiPhen BAMP DAMP Penetrances MultiPhen BAMP DAMP
0 (TIerror) both dominant 0.052 0.051 0.051 recessive,additive 0.054 0.052 0.052
0.33 (0.1, 0.1, 0.02) 0.32 0.31 0.33 (0.25, 0.08, 0.08) 0.11 0.11 0.12
0.66 (0.1, 0.1, 0.02) 0.88 0.87 0.88 (0.12, 0.08, 0.04) 0.28 0.29 0.31
0.95 0.99 0.99 0.99 0.50 0.53 0.55