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. Author manuscript; available in PMC: 2017 Apr 13.
Published in final edited form as: Small. 2016 Feb 17;12(14):1891–1899. doi: 10.1002/smll.201502120

Figure 6.

Figure 6

Blood biopsies (1ml volume) from prostate patients with metastatic castration resistant cancer were magnetically labeled with 1μm αEpCAM particles and cells were separated on the ratcheting cytometry system. (a) Patients 46.1 and 10.3 had several cells (N=7 and N=8 CTCs respectively) which equilibrated between the 70–100μm pitches with purity ranging from 50% to 100%. In contrast, patient 43.2 exhibited no cells in the 70–100μm pitches and a skewed cumulative population towards the lower pitches. Suspected prostate CTCs extracted from patients 10.3 (b) possessed morphological characteristics consistent with CTCs including large nuclear to cytoplasmic ratio, and large lobed or multiple nuclei in addition to being CD45 negative.