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Compound 1 inhibits growth of MDA-MB-468 xenografts. (A) Caliper measurements of tumor volumes taken twice weekly over the course of treatment with 1 (maximiscin). Results represent median ± interquartile range (IQR) for n = 8 (Ctrl) or 7 (treated) tumors. (B) Comparison of final tumor volumes on day 21 of treatment; one-tailed Mann-Whitney rank analysis. (C) Percent change in mouse weights over the course of treatment. Results represent mean ± SD.
